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Index > Protein center > Hmmr(Gene name) > Mouse
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  • Hmmr (Gene name),
  • Hyaluronan mediated motility receptor (Protein name ),  HMMR_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Hmmr(Ihabp;Rhamm);
    Protein name:
    Hyaluronan mediated motility receptor;
    Alternative:
    Receptor for hyaluronan-mediated motility;Intracellular hyaluronic acid-binding protein;
    CD:
    CD168;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Subunit of the HARC complex.
    Function:
    Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.
    Subcellular Location:
    Cell surface Cytoplasm
    Protein Attributes:
    Sequence length:
    794
    Sequence:
    50:
    MSFPKAPLKR | FNDPSGCAPS | PGAYDVKTSE | ATKGPVSFQK | SQRFKNQRES | 
    100:
    QQNLNIDKDT | TLLASAKKAK | KSVSKKDSQK | NDKDVKRLEK | EIRALLQERG | 
    150:
    TQDKRIQDME | SELEKTEAKL | NAAVREKTSL | SASNASLEKR | LTELTRANEL | 
    200:
    LKAKFSEDGH | QKNMRALSLE | LMKLRNKRET | KMRSMMVKQE | GMELKLQATQ | 
    250:
    KDLTESKGKI | VQLEGKLVSI | EKEKIDEKCE | TEKLLEYIQE | ISCASDQVEK | 
    300:
    CKVDIAQLEE | DLKEKDREIL | SLKQSLEENI | TFSKQIEDLT | VKCQLLETER | 
    350:
    DNLVSKDRER | AETLSAEMQI | LTERLALERQ | EYEKLQQKEL | QSQSLLQQEK | 
    400:
    ELSARLQQQL | CSFQEEMTSE | KNVFKEELKL | ALAELDAVQQ | KEEQSERLVK | 
    450:
    QLEEETKSTA | EQLTRLDNLL | REKEVELEKH | IAAHAQAILI | AQEKYNDTAQ | 
    500:
    SLRDVTAQLE | SVQEKYNDTA | QSLRDVTAQL | ESEQEKYNDT | AQSLRDVTAQ | 
    550:
    LESEQEKYND | TAQSLRDVTA | QLESVQEKYN | DTAQSLRDVT | AQLESYKSST | 
    600:
    LKEIEDLKLE | NLTLQEKVAM | AEKSVEDVQQ | QILTAESTNQ | EYARMVQDLQ | 
    650:
    NRSTLKEEEI | KEITSSFLEK | ITDLKNQLRQ | QDEDFRKQLE | EKGKRTAEKE | 
    700:
    NVMTELTMEI | NKWRLLYEEL | YEKTKPFQQQ | LDAFEAEKQA | LLNEHGATQE | 
    750:
    QLNKIRDSYA | QLLGHQNLKQ | KIKHVVKLKD | ENSQLKSEVS | KLRSQLVKRK | 
    794:
    QNELRLQGEL | DKALGIRHFD | PSKAFCHASK | ENFTPLKEGN | PNCC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Hyaluronan mediated motility receptor
    Cat.:
    E9486h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Hyaluronan mediated motility receptor
    Cat.:
    E9486r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse Hyaluronan mediated motility receptor
    Cat.:
    E9486m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse Hyaluronan mediated motility receptor
    MSDS:
    Please sign in first.
    CLIA Kit for Mouse Hyaluronan mediated motility receptor
    Cat.:
    U9486h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse Hyaluronan mediated motility receptor
    Cat.:
    U9486m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Cat.:
    P9486Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Polyclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Cat.:
    P9486Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Monoclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Monoclonal Antibody for Mouse Hyaluronan mediated motility receptor
    Protein for Mouse Hyaluronan mediated motility receptor
    Protein for Mouse Hyaluronan mediated motility receptor
    Protein for Mouse Hyaluronan mediated motility receptor

    R&D Technical Data

             12% SDS-PAGE Analysis

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision

    Intra-assay Precision (Precision within an assay):Three samples of known concentration were tested twenty times on one plate to assess intra-assay precision.

    Intra-Assay CV: ≤4.3%

    Inter-assay Precision (Precision between assays):Three samples of known concentration were tested in five separate assays to assess inter-assay precision.

    Inter-Assay CV: ≤8.5%

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery

    Recovery was determined by spiking various levels of ACE into serum and plasma .

    Sample Type

    Average(%)

    Recovery Range(%)

    Serum

    99

    91-106

    Plasma

    99

    90-107

     

     

     

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Linearity

     

    The linearity of the kit was assayed by testing samples spiked with appropriate concentration of ACE and their serial dilutions. The results were demonstrated by the percentage of calculated concentration to the expected.  

     

    Sample

    1:2

    1:4

    1:8

    1:16

    serum(n=5)

    90-99%

    92-101%

    92-102%

    92-106%

    EDTA plasma(n=5)

    92-98%

    94-105%

    90-101%

    95-107%

    heparin plasma(n=5)

    94-104%

     

    94-108%

    101-107%

    93-109%

     

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Identification of IHABP, a 95 kDa intracellular hyaluronate binding protein."
      Hofmann M. , Fieber C. , Assmann V. , Goettlicher M. , Sleeman J. , Plug R. , Howells N. , von Stein O. , Ponta H. , Herrlich P.
      J. Cell Sci.111:1673-1684(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION
      tissue: Lung.
    2. 2.
      Zhao Y. , Zhang S. , Turley E.
      Submitted (1998-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    4. 4.
      Mural R.J. , Adams M.D. , Myers E.W. , Smith H.O. , Venter J.C.
      Submitted (2005-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Characterization of the murine gene encoding the intracellular hyaluronan receptor IHABP."
      Fieber C. , Plug R. , Sleeman J. , Dall P. , Ponta H. , Hofmann M.
      Gene226:41-50(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-183;TISSUE SPECIFICITY
      strain: 129/Sv.
    6. 6.
      "Characterization of the murine gene encoding the hyaluronan receptor RHAMM."
      Entwistle J. , Zhang S. , Yang B. , Wong C. , Li Q. , Hall C.L. , Jingbo A. , Mowat M. , Greenberg A.H. , Turley E.A.
      Gene163:233-238(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 164-794;ALTERNATIVE SPLICING
      strain: BALB/c.
      tissue: Fibroblast.
    7. 7.
      "Molecular cloning of a novel hyaluronan receptor that mediates tumor cell motility."
      Hardwick C. , Hoare K. , Owens R. , Hohn H.P. , Hook M. , Moore D. , Cripps V. , Austen L. , Nance D.M. , Turley E.A.
      J. Cell Biol.117:1343-1350(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 318-794;CHARACTERIZATION
      strain: BALB/c.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    9. 9.
      "Hyaluronan and the hyaluronan receptor RHAMM promote focal adhesion turnover and transient tyrosine kinase activity."
      Hall C.L. , Wang C. , Lange L.A. , Turley E.A.
      J. Cell Biol.126:575-588(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
    10. 10.
      "The hyaluronan receptor RHAMM regulates extracellular-regulated kinase."
      Zhang S. , Chang M.C. , Zylka D. , Turley S. , Harrison R. , Turley E.A.
      J. Biol. Chem.273:11342-11348(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERK REGULATION;SUBCELLULAR LOCATION
    11. 11.
      "Problems with RHAMM: a new link between surface adhesion and oncogenesis?"
      Hofmann M. , Assmann V. , Fieber C. , Sleeman J.P. , Moll J. , Ponta H. , Hart I.R. , Herrlich P.
      Cell95:591-592(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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